1. Glutamine. 50 grams a day in juice. 25 grams twice a day. See our homepage supplement file for bulk purchase options.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/04/he-just-stopped.html

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/04/glutamine-deple.html

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/04/glutamine-dep-1.html

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/04/glutamine-defic.html

2.  Sodium Selenite. 200 micrograms five times a day. 1 mg total per day.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/03/sodium-selenite.html

3. Lithium orotate. Dosages are listed below.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/03/lithium-is-a-po.html

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/03/autophagy-lithi.html

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/03/gsk3-nf-kappab.html

4. Methyl Jasmonate. 2 grams five times a month via aerosol inhalation. MJ can also be administered in a 70% DMSO gel directly into the hair follicles of the arm pit (for introduction into the lymphatic system), on the scrotum for the treatment of prostate cancer, or directly on surface cancers such as skin and breast cancer.

MJ is expensive and it is getting more expensive. The wholesale price for one kilogram increased by $700 in two months. I use this product in my skin cream SkinAlive. I will sell it to anyone who wants it for $170/10 grams. Send the money via PayPal to smartin@grouppekurosawa.net. MJ is one of the most potent anti-cancer agents known.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/04/methyl-jasmonat.html

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/04/methyl-jasmon-1.html

5. Sulindac. This inexpensive anti-inflammatory prescription drug powerfully activates a "magic bullet" death pathway that promotes autophagy. Sulindac also inhibits Cox-2, AKT, STAT3 and NF-kappaB signaling. In addition, sulindac is a TRUE histone deacetylase inhibitor. The dose is 200 mgs three times a day, 600 mgs total.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2006/07/sulindac_an_old.html

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/04/the-anti-inflam.html

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/02/sulindac-is-a-s.html

A non-prescription source of sulindac is available at a reasonable price.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/05/sulindac-source.html

6. Isoleucine. 10 grams a day. 5 grams twice a day. This is a minimal dose. The amino acid isoleucine inhibits the synthesis of VEGF, a growth factor which promotes the development of blood vessels into tumors and sites of inflammation.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/03/the-amino-acid.html

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/03/the-anti-cancer.html

The following is our new bulk source for isoleucine.

http://www.nutrabio.com/Products/isoleucine.htm

7. Metformin. This common anti-diabetes drug is a powerful activator of the AMP kinase. This kinase activates autophagy, our preferred form of programmed cell death.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/03/metformin-activ.html

This drug can be purchased from an online pharmacy without a prescription.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/05/non-prescriptio.html

The dose is 2 grams a day, 1 gram in the morning and 1 gram in the evening.

The use of metformin must be accompanied by vitamin B12 and calcium supplements.

http://www.lef.org/magazine/mag2007/aug2007_atp_01.htm

8. Policosanol. This supplement is a powerful inducer of autophagy via the activation of AMP kinase. The daily dose is 20 mgs a day, taken at night.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/04/the-supplement.html

9. DCA, 12mgs/kilo of body weight every OTHER day. Take it as one dose in the morning. Dissolve in juice or water. DCA should NOT be used to treat brain cancer.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/03/dca-availabilit.html

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/03/caffeine-enhanc.html

DCA is largely unavailable to US citizens because the FDA has banned its use.

10. Caffeine. See essay above. Caffeine enhances the efficacy of DCA. Consume as much as you can stand.

Caffeine is also an mTOR inhibitor. The combination of mTOR and glycolysis inhibitors powerfully promotes programmed cell death. MTOR is the natural inhibitor of autophagy.

http://www.ncbi.nlm.nih.gov/entrez/queryd.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=15459249&itool=pubmed_docsum

11.  Vitamin B1. 1 gram a day. Vitamin B1 combined with DCA, and caffeine is synergistic in their ability to kill cancer cells.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/03/vitamin-b1-thia.html

12. Sodium salicylate. 1 tablespoon a day in water or juice. Take as much as you can stand. It is a remarkable natural medicine. I have written many blog essay on SS. Conduct a search on this blog for the relevant essays.

13. Vitamin D3. 10,000IU a day, 5000IU twice a day. Vitamin D is a well established anti-cancer hormone. Due to our lack of exposure to ultraviolet light and the lack of vitamin D in our diet, supplemental vitamin D is essential for good health.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/03/the-antagonism.html

Vitamin D sources include LEF.org (order from our home page). This vitamin D must be dissolved in oil before ingesting. Another source is vitamin D3 encapsuled in olive oil.

http://www.carlsonlabs.com/product_detail.phtml?prodid=10001068&categid=0004

14. Vitamin A. 50,000IU a day. Vitamin A promotes the synthesis of TRAIL and other anti-cancer compounds.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2007/05/vitamin_a_trail.html

15. Melatonin. The World Health Organization now considers working the night shift a carcinogen. Melatonin is a known anti-cancer agent that is released from the brain at night in total darkness. Even a night light or a street light can inhibit melatonin synthesis. Women who work the night shift are particularly prone to developing breast cancer. Dose is 30-50 mgs a day, taken at night.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/01/the-night-shift.html

If you have a B cell lymphoma or leukemia, you should not take large doses of melatonin.

16. Amino Acids. The mTOR biochemical pathway blocks autophagy and promotes cancer cell survival. The amino acid glutamine inhibits mTOR while the amino acid leucine activates it.

http://grouppekurosawa.typepad.com/grouppe_kurosawa_natural_/2008/04/the-control-of.html

Of course, there are also dietary and supplement concerns. You cannot use omega 6 oils, such as corn, safflower or soy. They produce inflammatory prostaglandins in the body. You must also avoid supplements such as vitamin C, E, NAC (n-acetylcysteine), ALA (alpha lipoic acid). And stay away from high anti-oxidant fruit juices and foods. If you have cancer, anti-oxidants are not your friend.

Dropping your intake of sugar wouldn't hurt either.

Stay tuned...

Grouppe Kurosawa, Medicine in the Public Interest

http://www.grouppekurosawa.com